Moist Heat Sterilization uses moisture, water-vapor or steam at high temperatures and is achieved in an autoclave, an enclosed device that sterilizes products with pressurized steam. Typically, autoclaves are the preferred method of moist heat sterilization. The advantages of this type of sterilization are that the penetrating nature of steam makes it a great solution to destroy proteins in any microorganism after a certain amount of time. It is environmentally safe, having no toxic by-products. For some applications, such as with liquids or gels contained in sealed vessels, air-over pressure steam sterilization is available at Gibraltar. Typically the process involves method development followed by validation of the established load and cycle conditions.

Dry Heat Sterilization is typically achieved through methods such as use of a Hot Air Oven. The most commonly seen method of dry heat sterilization in the medical and pharmaceutical industry is the Hot Air Oven method. The dry heat sterilization is preferred for heat stable products that are sensitive to moisture.

Liquid Chemical Sterilization is typically used for devices, instruments and tools that are heat sensitive but not liquid sensitive. The object in need of sterilization is immersed in the sterilizing liquid for a set amount of time and then undergoes sterilization validation in order to assess whether it has been fully sterilized. Peracetic Acid, Glutaraldehyde or combination products are used for this process. Care must be taken to properly clean off these chemicals. The advantages of liquid Chemical Sterilization are that it is extremely effective at killing vegetative organisms and spores.

Conclusion These are just a few types of potential sterilization procedures that can be used by a pharmaceutical or medical company. There are a few others, including gas sterilization and radiation sterilization. These forms of sterilization will destroy living organisms but are also quite dangerous to people and the environment.

Choose Gibraltar Laboratories for Moist Heat Steam Sterilization/Dry Heat Sterilization/ Liquid Chemical Sterilization

At Gibraltar Laboratories, Inc. we have a full, comprehensive understanding of the appropriate sterilization procedures including moist heat steam sterilization, dry heat sterilization and liquid chemical sterilization. Count on Gibraltar Laboratories, Inc.  to know what kind of sterilization is right for each product.

Contact us today!

To learn more, please call us at (973)-227-6882.

Recent Blog Posts